[Polygenic scores and cancer risk].

Risk assessment for a cancer type with moderate heritability can be accurately performed using a relatively small number of SNPs detected by GWAS analyses to calculate a polygenic risk score (PRS) that has definite clinical utility.

Related Organizations

French National Centre for Scientific Research
France

Keywords

Multifactorial Inheritance, Medical Oncology, Polymorphism, Single Nucleotide, Research Design, Risk Factors, Case-Control Studies, Neoplasms, Biomarkers, Tumor, Humans, Genetic Predisposition to Disease, Thyroid Neoplasms, Genome-Wide Association Study

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