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Oral physiology and quality of life in cancer patients.

Authors: Pereira, Luciano J.; Braga Caputo, Júnior; Midori Castelo, Paula; Francelino Andrade, Eric; Silva Marques, Leandro; Martins de Paiva, Saul; Márcia Pereira, Stela; +1 Authors

Oral physiology and quality of life in cancer patients.

Abstract

Introdución: El tratamiento del cáncer puede afectar la salud de los dientes y estructuras de apoyo, que son esenciales para el proceso de masticación, que pueden cambiar el estado nutricional del paciente. Objetivo: El objetivo de este estudio fue evaluar el impacto de los cambios fisiológicos orales sobre la calidad de vida (QoL) de los pacientes sometidos a tratamiento contra el cáncer. Metodos: Inicialmente 84 pacientes con cáncer fueron examinados y sólo los que presentan al menos 15 dientes naturales fueron seleccionados para la fisiología oral y la calidad de las pruebas de la vida. La muestra final quedó conformado por 30 pacientes. Veinte sujetos fueron seleccionados como controles emparejados por edad y sexo. Dental estado de la caries, el flujo salival, rendimiento masticatorio (MP), la ubicación del tumor, la duración de la quimioterapia y la radioterapia y lo cuestionario de La Organización Mundial de la Salud Calidad de Vida (WHOQOL-BREF) cuestionario fueron evaluados. Se utilizaron modelos de regresión lineal para probar la relación entre los dominios del WHOQOL-BREF (psicológicos relación física,, social, ambiental y de calidad de vida en general) y variables independientes bajo estudio. Resultados y Discusión: Número de dientes, MP y el flujo salival fueron menores en los pacientes de cáncer, así como para las puntuaciones obtenidas en la relación social, medio ambiente y dominios de calidad de vida general (p <0,050). El cáncer de mama causó un impacto negativo en la psicológica (p <0,001) y las puntuaciones de calidad de vida global (p = 0,017). Un efecto negativo similar se encontró para la duración de la radioterapia sobre psicológica (p = 0,012) y ambientales (p = 0,039) dominios. Por otra parte, el mantenimiento de dientes tuvo un impacto positivo en la psicológica (p = 0,012) y del Medio Ambiente (p = 0,024) resultados. Conclusión: los cambios orales fisiología pueden afectar la calidad de vida de los pacientes oncológicos. El mantenimiento de dientes fue de importancia positiva, sobre todo por los aspectos psicológicos.

Introduction: Cancer treatment can affect the health of the teeth and support structures, which are essential to the chewing process, which may change the nutritional status of the patient. Objective: The aim of this study was to evaluate the impact of oral physiology changes on quality of life (QoL) of patients submitted to cancer treatment. Design: Initially 84 cancer patients were screened and only those presenting at least 15 natural teeth were selected for oral physiology and quality of life tests. The final sample comprised 30 patients. Twenty subjects were selected as controls paired by age and gender. Dental caries status, salivary flow, masticatory performance (MP), location of tumor, duration of chemo and radiotherapy and World Health Organization Quality of Life (WHOQOL- bref) questionnaire were assessed. Linear regression models were used to test the relationship between the WHOQOL-bref domains (physical, psychological, social relationship, environmental and overall QoL) and independent variables under study. Results and Discussion: Number of teeth, MP and salivary flow were lower in cancer patients, as well as for the scores obtained in Social Relationship, Environment and Overall QoL domains (p<0.050). Breast cancer caused a negative impact on Psychological (p<0.001) and Overall QoL scores (p=0.017). A similar negative effect was found for the duration of radiotherapy on Psychological (p=0.012) and Environmental (p=0.039) domains. On the other hand, the maintenance of teeth had a positive impact on Psychological (p=0.012) and Environmental (p=0.024) scores. Conclusion: Oral physiology changes may impact the QoL of oncological patients. The maintenance of teeth was of positive importance, especially for the psychological aspects.

Keywords

Quality of life, Adult, Male, Sabor, Oral Health, Dental Caries, Social Environment, Oncología, La quimioterapia, Neoplasms, Chemotherapy, Humans, Masticatory Performance, Aged, Middle Aged, La calidad de vida, Cross-Sectional Studies, Oncology, Taste, Rendimiento masticatorio, Quality of Life, Female, Tooth, Brazil

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
6
Average
Average
Top 10%
gold