Chiropractic is a regulated health profession currently serving approximately 10% of the Canadian population annually1 with the aim to improve the health and well-being of Canadians, primarily with musculoskeletal disorders. Despite available evidence for optimal management of these disorders,2–4 poor adherence to guidelines and wide variations in service delivery by clinicians have been noted across health care disciplines,3,5 including chiropractic.6,7 Efforts to embrace and enhance evidence-based practice among chiropractors and develop opportunities for multi-disciplinary research collaboration have been hampered by a number of issues. Issues include: 1) limited research capacity in chiropractic with less than 1% of the chiropractic profession conducting research;8 2) fragmented integration of chiropractic into the health care system that has been hampered by discrepancies among practising chiropractors, chiropractic researchers, and regulatory bodies over scope and paradigm of practice (alternative or empiricist/experiential-based vs. evidence-based practice);9,10 3) over half of chiropractors are in solo practice11 with solo providers having greater variation in accepted clinical practices;12 and 4) perceived suboptimal coordination of efforts from professional associations, regulatory boards and chiropractic teaching institutions to successfully implement evidence into practice. One strategy to address these issues is the creation of practice-based research networks (PBRNs). Primary care PBRNs bring together researchers and groups of clinicians and practices with the goal of improving health services delivery and closing the gap between research and practice.13–16 The general aim is to stimulate the development of appropriate research that reflects the context of healthcare practice in a primary care setting.