Malocclusion should be identified at its earliest before it produces any detrimental effects. The objective of this study is to evaluate the orthodontic status and treatment need of school children in Telangana region, Andhra Pradesh, using Dental Aesthetic Index.One thousand children in the age group of 12 - 14 years who fulfilled the inclusion and exclusion criteria were considered. The demographic details of the students along with the information on the orthodontic status were collected using a predesigned questionnaire by a single orthodontist. The information on orthodontic status was obtained using Dentofacial Anomalies with the criteria of Dental Aesthetic Index (W H O Oral Health Assessment form 1997).RESULTS were subjected to ANOVA, Tukeys test and chi square test using SPSS, version 16. 86.1% of the subjects had DAI score of less than 25, suggesting 'no treatment'; 10% had DAI score of 26-30, suggesting 'elective treatment'; 3% had DAI score of 31-35, suggesting 'highly desirable treatment'; 0.9% had DAI score of >36, indicating 'mandatory treatment'; Higher prevalence of malocclusion among females than males.It is necessary to identify this abnormality at its earliest before it produces detrimental effects. It is also essential to know the prevalence of malocclusion in any society, as it reveals the true extent of the problem and guides in overcoming it. The general public can, then, be educated on widespread occurrence of malocclusion and its deleterious effects, so that appropriate preventive and corrective measures can be instituted. How to cite this article: Anita G, Kumar GA, Reddy V, Reddy TP, Rao MS, Wankhade SB. Dental Aesthetic Index of school students in Telangana region - An epidemiological study. J Int Oral Health 2013; 5(6):55-60 .