Hepatitis C is an infectious disease affecting the liver, caused by the hepatitis C virus (HCV). The infection is often asymptomatic, but once established, chronic infection can progress to scarring of the liver (fibrosis), and advanced scarring (cirrhosis) which is generally apparent after many years. The main goal of this work is the investigation of the important factors that affect hepatitis C. Epidemiological and Statistical analysis using non-parametric tests (Kruskal-Willis, Mann-Whitney) are considered to present the amount of significant differences between important factors. Proposed model are analyzed when logistic regression is applied.