Fluorine-18 chemistry in micro-reactors.
Copyright policy ) Shuiyu, Lu; Joong-Hyun, Chun; Victor W, Pike;
Fluorine-18 chemistry in micro-reactors.
Recent applications of micro-reactor (microfluidics) technology to radiofluorination chemistry within our laboratory are presented, based on use of either a simple T-shaped glass micro-reactor or a more advanced microfluidics instrument. The topics include reaction optimization and radioligand production, in particular the study of the radiofluorination of diaryliodonium salts, [(18)F]fluoride ion exchange with xenon difluoride(,) esterification with [(18)F]2-fluoroethyl tosylate, and the syntheses of [(18)F]fallypride, [(18)F]FBR and [(18)F]SL702 from [(18)F]fluoride ion.
- National Institutes of Health United States
- National Institute of Mental Health United States
This action will publish the selected files and record in Zenodo. Are you sure you want to proceed?