
handle: 2078.1/254835
Polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy and skin changes (POEMS) syndrome is a rare disorder due to an underlying plasma cell clone (PC). The syndrome can affect several organs. The diagnosis is based on the presence of mandatory criteria (polyneuropathy, monoclonal plasma cell disorder) and at least one major and one minor criteria. The therapeutic regimen is determined according to the extent of the patient’s sclerotic lesions and the presence of bone marrow involvement.
osteosclerotic bone lesion, polyneuropathy., monoclonal protein, POEMS
osteosclerotic bone lesion, polyneuropathy., monoclonal protein, POEMS
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