The aim of this research is to examine the relationships between self-compassion and relational-interdependent self-construal. The participants were 338 university students. In this study, the Self-Compassion Scale and the Relational-Interdependent Self-Construal Scale were used. The relationships between self-compassion and relational-interdependent self-construal were examined using correlation analysis and multiple regression analysis. In correlation analysis, self-kindness, common humanity, and mindfulness factors of self-compassion were found positively related to relational-interdependent self-construal. On the other hand, self-judgment, isolation, and over-identification factors of self-compassion were found negatively correlated to relational-interdependent self-construal. Multiple regression analysis showed that relational-interdependent self-construal was predicted positively only by common humanity. However, relational-interdependent self-construal was negatively explained by isolation, self-judgment, and over-identification, According to standardized beta coefficients, the most significant predictor of relational-interdependent self-construal was isolation. Results were discussed in the light of the related literature.