This article describes a technique used to treat superficial white spot lesions by a minimally invasive approach. The proposed technique is based on reactivation of enamel by elimination of its hypermineralized external layer through microabrasion, followed by daily home application of casein phosphopeptide-amorphous calcium phosphate complexes (CCP-ACP). The technique may allow elimination of white spot lesions without involving restorative procedures. Microabrasion followed by long-term daily home application of CCP-ACP may be considered an interesting alternative to the restorative approach for treatment of white spot lesions.