The objective of this study is to describe the experience at the Federal University of São Carlos concerning the mandatory discipline Nursing and Workers' Health, taught at the undergraduate course in Nursing, which focuses on the activities that concern workers' health surveillance. As a teaching strategy, an epidemiological analysis of all labor accidents registered at the local agency of the social security system referring to the municipality of São Carlos, State of São Paulo, in the year of 2000 was carried out. Based on this information system the students developed practical activities related to the organization of the data and the use of the software to insert, consolidate and analyze the information. Besides this, themes concerning workers' health surveillance and related issues have been developed. The results obtained in these activities have been evaluated and are discussed in this article.