Epidemiological evidence suggests that diets rich in fruits and vegetables decrease the risk of premature mortality from major clinical conditions, including cancer and heart disease. However, it is not yet clear which components or combination of components in fruit and vegatables are protective and what is their mechanism of action is. Phenolic compounds are important compounds because of their contribution to human health and their multiple biological activities. Although these compounds are not a panacea for good health, some of their beneficialt activities presented in this short review showed their importance and their possible usage in the prevention of various diseases (Tab. 1, Fig. 1, Ref: 42).