
Palonosetron, a selective 5-HT3 receptor antagonist, is being developed by Helsinn for the potential treatment of chemotherapy-induced nausea and vomiting. By 1999, it was in phase III trials, and as of May 2002, an NDA filing was scheduled for the third quarter of 2002.
Palonosetron, Clinical Trials as Topic, Quinuclidines, Structure-Activity Relationship, Animals, Antiemetics, Humans, Serotonin Antagonists, Isoquinolines
Palonosetron, Clinical Trials as Topic, Quinuclidines, Structure-Activity Relationship, Animals, Antiemetics, Humans, Serotonin Antagonists, Isoquinolines
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