The paper makes some references to the documentary funds for malaria history retained in state and private archives. The most important are seven: the State archives of Cagliari, Sassari, Nuoro, the Provincial administration archive of Sassari, the ERLAAS (Ente regionale per la lotta antianofelica in Sardegna) archive. The private archives are deposited in town libraries of Iglesias and Olzai. The documentation available allows to carry out a lot of research on various courses; a) activity of land reclamation on marshy zones between XIX and XXth century; b) issues of the anti-malarial legislation in the early twentieth century for peculiar social classes such as railwaymen and miners. They were the first to assay the quinine for preventive treatment; c) the anti-anopheles struggle during the Fasciste regime (it was carried out with oil and Paris green and with the predator fish of the genus Gambusia as well) d) organization of anti-anopheles campaign of ERLASS after World War II.