: The purpose of the present study was to analyze the effect of perceptions of neighborhood danger on positive parenting and whether it is mediated by the mothers' perceived self-efficacy in managing negative emotions, comparing two countries: Colombia and Italy. Participants were 434 mothers and children between ages of 8 and 10 years old (108 dyads from Medellin, Colombia and 109 dyads from Rome, Italy). selected by convenience, non-probabilistically and proportionally to the social stratum of each city. Mothers and children answered the neighborhood violence perception scale, mothers also answered the emotional self-efficacy scale and children the Acceptance-Rejection/Control questionnaire. The multigroup analysis found that mothers' self-efficacy in managing negative emotions behaved differently in Colombia compared to Italy. In Colombia, mothers' perceived self-efficacy in managing negative emotions mediated the link between the effect of perceived neighborhood violence and the quality of mother-child relationship. In Italy, mothers' self-efficacy in managing negative emotions did not mediate this link. Perceived self-efficacy in managing negative emotions of Colombian mothers indirectly explains the adverse effect of perceived neighborhood danger on positive parenting. With mothers from Rome-Italy, there is no significant relationship between perceived self-efficacy for the management of negative emotions and positive parenting.