Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ LAReferencia - Red F...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
versions View all 1 versions
addClaim

Estudo das alterações estruturais e da função diastólica cardíaca em mulheres portadoras de diabetes melito gestacional

Authors: Oliveira, Alexandra Paula de;

Estudo das alterações estruturais e da função diastólica cardíaca em mulheres portadoras de diabetes melito gestacional

Abstract

Background: Gestational Diabetes Mellitus (GDM) is a risk condition for developing type 2 diabetes and its possible future developments. It is considered an independent risk factor for cardiovascular disease, the leading cause of death among diabetic patients. Objective: To identify and compare the structural and diastolic function in pregnant women with gestational diabetes mellitus and healthy pregnant women and verify possible correlation between clinical and biochemical variables with maternal ventricular mass index (LVMI) and the ratio of peak of transmitral diastolic flow velocity in early diastole (E') and peak velocity of transmitral diastolic flow during atrial contraction (A'). Subject and Methods: This was a prospective cross-sectional study in women with GDM (n = 21) and healthy pregnant women (n = 23). All the women underwent echocardiography between the 34th. and the 37th. weeks of gestation, and the results were statistically analyzed for comparison between groups, adopting the threshold of significance of 95% (p <0.05). Results: Clinical features and biochemical variables, values for age, parity, body mass index gestational and before pregnancy, fasting glucose and hemoglobin A1c were significantly higher in GDM group. Posterior wall thickness, interventricular septum, LV mass and LV mass index were significantly higher in GDM group. The E’ and E'/A' were significantly lower in the GDM group, which also showed a positive correlation between LVMI, fasting glucose and pregnancy body mass index. Conclusion: Pregnant women with GDM have different diastolic profile, near to dysfunctional pattern, but within the range of normal values for the parameters studied. Even so, as the dysfunctional pattern tends to evolve with advancing age, it is recommended to these women more rigorous monitoring of glycemic control and cardiovascular system

Introdução: Diabetes Melito Gestacional (DMG) constitui risco para desenvolver diabetes melito tipo 2 e os seus possíveis desdobramentos futuros. É considerado fator de risco independente para doença cardiovascular, a principal causa de morte entre a população diabética. Objetivos: Identificar e comparar as alterações estruturais e da função diastólica cardíaca em gestantes portadoras de diabetes gestacional e gestantes sem patologias, e verificar se existem correlações entre características clínicas e variáveis bioquímicas maternas com o índice de massa ventricular (iMVE) e a razão entre pico de velocidade do fluxo diastólico transmitral no início da diástole (E’) e pico de velocidade do fluxo diastólico transmitral durante a contração atrial (A’). Sujeitos e Métodos: Foi realizado estudo prospectivo e transversal em gestantes com DMG (n=21) e gestantes sem patologias (n=23). Todas as gestantes realizaram ecocardiograma entre a 34ª. e a 37ª. semanas de gestação, cujos resultados foram analisados estatisticamente para comparação entre os grupos estudados, adotando-se o limite mínimo de significância de 95% (p<0,05). Resultados: Entre as características clínicas e variáveis bioquímicas estudadas, os valores de idade, paridade, índice de massa corpórea pré-gestacional e gestacional, glicemia de jejum e hemoglobina glicada foram significativamente maiores no grupo DMG. Das variáveis estruturais, a espessura da parede posterior, do septo interventricular, a massa do VE e o iMVE foram significativamente maiores ...

Pós-graduação em Ginecologia, Obstetrícia e Mastologia - FMB

Country
Brazil
Keywords

Diabetes na gravidez, Gravidez, Diagnóstico por imagem, Coração - Doenças, Diabetes in pregnancy

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green