PPAR gamma: an essential role in metabolic control.
Copyright policy )PPAR gamma: an essential role in metabolic control.
The peroxisome proliferator-activated receptor gamma is a nuclear hormone receptor playing a crucial role in adipogenesis and insulin sensitization. Prostaglandin J2 derivatives and the antidiabetic thiazolidinediones are its respective natural and synthetic ligands. The RXR/PPAR gamma heterodimer has also been reported to have important immunomodulatory activities and its pleiotropic functions suggest wide-ranging medical implications.
Inflammation, Arteriosclerosis, Prostaglandin D2, Gene Expression, Receptors, Cytoplasmic and Nuclear, Ligands, [SDV] Life Sciences [q-bio], Thiazoles, Adipose Tissue, Animals, Humans, Insulin, Thiazolidinediones, Transcription Factors
Inflammation, Arteriosclerosis, Prostaglandin D2, Gene Expression, Receptors, Cytoplasmic and Nuclear, Ligands, [SDV] Life Sciences [q-bio], Thiazoles, Adipose Tissue, Animals, Humans, Insulin, Thiazolidinediones, Transcription Factors
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