SUMMARY The authors surveyed 15 large-scale Hungarian cattle herds (13 dairies and 2 beef herds) in 2013 in terms of prophylaxis (vaccination and medication) against Bovine Respiratory Disease Complex (BRDC). From more than half of the herds Mannheimia haemolytica, BRSV, PI3 and Pasteurella multocida were identified. In the majority of dairy herds vaccinations were applied against BRSV, PI3, BVD and Mannheimia, beside the mandatory IBR marker vaccination. The macrolids were the mostly used antibiotics against BRDC (in more than 90% of the herds), followed by amoxicillin, enfrofloxacin and marbofloxacin (on half of the farms). Metaphylaxis was practised on around 30% of the farms.