Despite the increasing academic interest in the sensory dimension of the tourist experience, the quantitative empirical research in the field is limited by a lack of measurement instruments for evaluating the sensory stimuli perceived by tourists during a destination visit. The study addresses this gap by developing a composite index to assess the sensory destination panorama, termed as “destination sensescape”. The construct is conceptualised as a formative multidimensional variable with 5 dimensions (visualscape, smellscape, tastescape, soundscape, and hapticscape). The psychometric validity and reliability of the 17 items integrating the formative index were established by a rigorous multi-step procedure based on three empirical studies. The instrument was tested with data collected from visitors of a Mediterranean urban destination. The operationalisation of the destination sensescape construct not only paves the way for future quantitative sensory studies, but also yields a useful tool for Destination Marketing Organisations (DMOs).