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Flavonoides y enfermedad inflamatoria intestinal

Authors: Ballester, I.; Camuesco, D.; Gálvez, J.; Sánchez De Medina López-Huertas, Fermín; Zarzuelo Zurita, Antonio;

Flavonoides y enfermedad inflamatoria intestinal

Abstract

Epidemiological studies have revealed the important role that foodstuffs of vegetable origin have to play in the prevention of numerous illnesses. The natural antioxidants present in such foodstuffs, among which the fl avonoids are widely present, may be responsible for such an activity. Flavonoids are compounds that are low in molecular weight and widely distributed throughout the vegetable kingdom. They may be of great utility in states of accute or chronic diarrhoea through the inhibition of intestinal secretion and motility, and may also be benefi cial in the reduction of chronic infl ammatory damage in the intestine, by affording protection against oxidative stress and by preserving mucosal function. For this reason, the use of these agents is recommended in the treatment of infl ammatory bowel disease, in which various factors are involved in extreme immunological reactions, which lead to chronic intestinal infl ammation.

Estudios epidemiológicos han puesto en evidencia el papel que tienen los alimentos de origen vegetal en la prevención de numerosas enfermedades. Los antioxidantes naturales presentes en estos alimentos, entre los que destacan los fl avonoides, pueden ser responsables de esta actividad. Los fl avonoides son compuestos de bajo peso molecular que se encuentran ampliamente distribuidos en el reino vegetal. Pueden mejorar los estados de diarrea aguda y crónica a través de la inhibición de la secreción y motilidad intestinal y también ser muy útiles en la reducción del daño infl amatorio crónico en el intestino, protegiéndolo del estrés oxidativo y preservando la función de la mucosa. Por ello, se proponen como agentes terapéuticos en el tratamiento de la Enfermedad Infl amatoria Intestinal, en la que factores diversos promueven una reacción inmunológica exacerbada que conduce a una infl amación crónica del intestino.

Country
Spain
Keywords

Flavonoids, Citocina, Leukotriene B4, Intestinal Inflammatory disease, Enfermedad Inflamatoria Intestinal, Flavonoide, Antioxidante, Cytocine, Nitric acid, Antioxidant, Óxido nítrico, Leucotrieno B4, NFκB

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green