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Estudo Geral
Doctoral thesis . 2008
Data sources: Estudo Geral
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Skin structure and drug permeation

Authors: Silva, Cláudia Liliana de Bastos Sousa;

Skin structure and drug permeation

Abstract

A administração transdérmica de fármacos constitui uma via de administração de moléculas activas através da pele, inovadora, não invasiva, permite controlar o efeito de primeira passagem hepática, promove a adesão à terapêutica e reduz os efeitos adversos quando comparada com as vias mais tradicionais. Apesar das inúmeras vantagens, a sua aplicação encontra-se limitada pela grande resistência da pele à penetração de fármacos. ... Em face destas características, os objectivos deste trabalho são a investigação da organização estrutural da camada exterior da pele (camada córnea) e o desenvolvimento de uma nova forma farmacêutica para a administração transdérmica de fármacos. ...

Trabalho financiado pela Fundação para a Ciência e Tecnologia - Bolsa de doutoramento

Country
Portugal
Related Organizations
Keywords

Epiderme, permeabilidade, Administração cutânea, Pele, fisiologia, Tecnologia farmacêutica, Formas farmacêuticas, Sistemas de libertação de medicamentos

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    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Green