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Estudo Geral
Master thesis . 2025
Data sources: Estudo Geral
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Relatórios de Estágio e Monografia intitulada " Plantas e seus metabolitos bioativos como alternativas naturais no controlo da sudorese e do odor corporal"

Authors: Correia, Daniela Maria Mendes;

Relatórios de Estágio e Monografia intitulada " Plantas e seus metabolitos bioativos como alternativas naturais no controlo da sudorese e do odor corporal"

Abstract

A sudorese é um mecanismo fisiológico essencial à termorregulação e à homeostase hidroeletrolítica, assegurando também funções de defesa cutânea e de excreção de metabolitos. A sua desregulação pode originar patologias como hiperidrose e osmidrose, com impacto relevante na saúde física, psicológica e social dos indivíduos. As terapêuticas convencionais, embora eficazes, apresentam limitações devido a efeitos adversos, risco de toxicidade e impacto na microbiota cutânea. Neste contexto, a fitoterapia surge como alternativa ou adjuvante promissora, recorrendo a metabolitos bioativos de plantas medicinais com propriedades adstringentes, antimicrobianas, anti-inflamatórias e reguladoras da atividade glandular. A investigação científica tem demonstrado que compostos como taninos, flavonoides, ácidos fenólicos e óleos essenciais apresentam atividade relevante no controlo da produção de suor e na redução do odor corporal, podendo atuar na modulação da atividade das glândulas sudoríparas ou na inibição do crescimento microbiano responsável pela degradação dos componentes do suor. Este potencial terapêutico alia-se ao interesse crescente por formulações mais seguras, eficazes e ambientalmente sustentáveis, que respeitem a fisiologia cutânea e reduzam a dependência de substâncias sintéticas, frequentemente associadas a efeitos adversos. Assim, esta revisão aborda os mecanismos da transpiração, as suas disfunções e a relevância dos extratos vegetais no desenvolvimento de novas estratégias terapêuticas e cosméticas para a sudorese e o odor corporal. O Mestrado Integrado em Ciências Farmacêuticas (MICF) constitui uma formação académica de elevada exigência técnico-científica, orientada para a preparação de profissionais de saúde altamente qualificados, com competências para intervir em todas as fases do ciclo do medicamento. A formação integra componentes teóricas, laboratoriais e práticas, que conferem ao futuro farmacêutico um perfil multidisciplinar, alinhado com as necessidades contemporâneas da prática farmacêutica.

Sweating is a physiological mechanism essential to thermoregulation and hydroelectrolytic homeostasis, also ensuring skin defense functions and metabolite excretion. Its deregulation can lead to pathologies such as hyperhidrosis and osmidrosis, with a relevant impact on the physical, psychological and social health of individuals. Conventional therapies, although effective, have limitations due to adverse effects, risk of toxicity and impact on the skin microbiota. In this context, phytotherapy emerges as a promising alternative or adjuvant, using bioactive metabolites of medicinal plants with astringent, antimicrobial, anti-inflammatory and glandular activity regulating properties. Scientific research has shown that compounds such as tannins, flavonoids, phenolic acids and essential oils have relevant activity in controlling sweat production and reducing body odor and may act in modulating the activity of sweat glands or in inhibiting the microbial growth responsible for the degradation of sweat components. This therapeutic potential is combined with the growing interest in safer, more effective and environmentally sustainable formulations that respect skin physiology and reduce dependence on synthetic substances, often associated with adverse effects. Thus, this review addresses the mechanisms of perspiration, its dysfunctions and the relevance of plant extracts in the development of new therapeutic and cosmetic strategies for sweating and body odor. The Integrated Master's Degree in Pharmaceutical Sciences (MICF) is an academic training of high technical-scientific demand, oriented to the preparation of highly qualified health professionals, with skills to intervene in all phases of the drug cycle. The training integrates theoretical, laboratory and practical components, which give the future pharmacist a multidisciplinary profile, aligned with the contemporary needs of pharmaceutical practice.

Relatório de Estágio do Mestrado Integrado em Ciências Farmacêuticas apresentado à Faculdade de Farmácia

Country
Portugal
Related Organizations
Keywords

natural formulations, hiperidrose, sweating, formulações naturais, phytotherapy, hyperhidrosis, metabolitos bioativos, bioactive metabolites, fitoterapia, sudorese

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average