By offering a fresh insight into looking at long-standing issues in the history of research on the Church Slavonic Bible, the article intends to promote more profitable studies rather than merely summarise previous investigations. This paper tackles the wide-ranging problem of ways in which to approach the textual transmission of the Church Slavonic Bible and how to come to terms with methodological challenges in order to overturn the previous mindset on producing scientifically valid and reliable critical editions of the Church Slavonic Bible.