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Bioactive peptides derived from the proteins of egg white by means of enzymatic hydrolysis

Authors: Miguel, Marta; López-Fandiño, Rosina; Recio, Isidra; Ramos González, María Mercedes; Aleixandre, Amaya;

Bioactive peptides derived from the proteins of egg white by means of enzymatic hydrolysis

Abstract

[ES] La invención consiste en la producción de ovoproductos conteniendo péptidos bioactivos a partir de clara de huevo sometida a un tratamiento enzimático. Dichos péptidos muestran actividad inhibidora de la enzima convertidora de angiotensina (actividad lECA) in vitro y/o actividad antihipertensiva en ratas y/o actividad antioxidante. Estos ovoproductos: los hidrolizados completos, las fracciones de los mismos de bajo peso molecular, o sus péptidos constituyentes, podrían utilizarse como sustancias terapéuticas con actividad lECA y/o con actividad antihipertensiva y/o con actividad antioxidante, ya sea como productos alimentarios funcionales, aditivos o ingredientes alimentarios, o productos farmacéuticos, para el tratamiento y/o prevención de la hipertensión arterial en todas sus formas en un ser humano o en un animal y para el tratamiento y/o la prevención de cualquier desorden asociado con la hipertensión arterial en un ser humano o en un animal.

[EN] The invention relates to the production of ovoproducts containing bioactive peptides from the egg white subjected to enzymatic treatment. Said peptides have an inhibiting activity of the angiotensin converting enzyme (ACE inhibiting activity) in vitro and/or anti-hypertensive activity in rats and/or antioxidant activity. Said ovoproducts, complete hydrolizates, the fractions thereof with low molecular weight or their constituent peptides could be used as therapeutic substances with ACE inhibiting activity and/or anti-hypertensive activity and/or anti-oxidant activity, either as functional food products, food additives or ingredients or pharmaceutical products for the treatment and/or prevention of hypertension in all its forms in humans or animals and for the treatment and/or prevention of any disorder associated with hypertension in humans or animals.

Fecha de presentación internacional: 23.07.2004. - Titular: Consejo Superior de Investigaciones Científicas (CSIC)

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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