Views provided by UsageCountsThe effect of human follicular fluid on bovine oocyte developmental competence and embryo quality
Copyright policy ) Valckx, S. D. M.; De Bie, J.; Michiels, E. D.; Goovaerts, I. G.; Punjabi, U.; Ramos-Ibeas, P.; Gutierrez-Adan, A.; +2 Authors
Valckx, S. D. M.; De Bie, J.; Michiels, E. D.; Goovaerts, I. G.; Punjabi, U.; Ramos-Ibeas, P.; Gutierrez-Adan, A.; Bols, P. E.; Leroy, J. L.;
The effect of human follicular fluid on bovine oocyte developmental competence and embryo quality
In this study, the hypothesis that embryo development during routine IVF procedures is determined by the pre-ovulatory follicular fluid composition was tested. Follicular fluid from women with obesity ('obese') and a 'positive' or 'negative' IVF outcome was added during the in-vitro maturation of bovine oocytes. 'Negative' and 'obese' follicular fluid reduced bovine embryo development, compared with laboratory control embryo development (P < 0.05 or P < 0.1). The addition of follicular fluid also altered bovine blastocyst gene expression. Furthermore, LDHA and PPARGC1B gene expression differed between follicular fluid groups. Data suggest that pre-ovulatory follicular fluid can potentially affect oocyte developmental competence and embryo quality. Furthermore, the bovine model may be used as a screening tool.
- Antwerp University Hospital Belgium
- University of Antwerp Belgium
In-vitro maturation, Embryo quality, L-Lactate Dehydrogenase, Gene Expression Profiling, Follicular fluid, Fertilization in Vitro, Follicular Fluid, Embryo Culture Techniques, Isoenzymes, Blastocyst, Gene Expression Regulation, IVF, Oocytes, Oocyte developmental competence, Animals, Humans, Cattle, Female, Lactate Dehydrogenase 5, Transcription Factors
In-vitro maturation, Embryo quality, L-Lactate Dehydrogenase, Gene Expression Profiling, Follicular fluid, Fertilization in Vitro, Follicular Fluid, Embryo Culture Techniques, Isoenzymes, Blastocyst, Gene Expression Regulation, IVF, Oocytes, Oocyte developmental competence, Animals, Humans, Cattle, Female, Lactate Dehydrogenase 5, Transcription Factors
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).22 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 10% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 10% views 42 - 42views
selected citations
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These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Citations provided by BIP!popularityPopularity provided by BIP!
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
Popularity provided by BIP!influenceInfluence provided by BIP!
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
Influence provided by BIP!impulseImpulse provided by BIP!
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
Impulse provided by BIP!viewsViews provided by UsageCounts
Views provided by UsageCounts 22
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