Downloads provided by UsageCountsGenomic analysis of European Drosophila melanogaster populations reveals longitudinal structure, continent-wide selection, and previously unknown DNA viruses
Copyright policy )DFG| unidentified ,
UKRI| Selective Impact of Transposable Elements in Drosophila melanogaster ,
EC| DROSADAPTATION ,
EC| MAIZEKEY ,
EC| SymbNET ,
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FWF| Population genetics of piRNAs in Drosophila ,
WT| Institutional Strategic Support Fund Phase2 FY2014/16 ,
AKA| The role of alternative splicing in adaptation to a changing environment ,
SNSF| The Role of Chromosomal Inversions in Clinal Adaptation ,
FWF| Keep cool: The Influence of Symbionts on Thermal Preference ,
SNSF| The Genomic Basis of Life History Adaptation ,
EC| IDEAL ,
EC| ComplexSex ,
NIH| Adaptation in 6 dimensions ,
NIH| The genetic and physiological architecture of rapid and cyclic adaptation ,
SNSF| Population Genomic Basis of Evolutionary Change in Drosophila Aging and Life History
Kapun, Martin; Barrón, Maite G.; Staubach, Fabian; Obbard, Darren J.; Wiberg, R. Axel W.; Vieira, Jorge; Goubert, Clément; +39 Authors
Kapun, Martin; Barrón, Maite G.; Staubach, Fabian; Obbard, Darren J.; Wiberg, R. Axel W.; Vieira, Jorge; Goubert, Clément; Rota-Stabelli, Omar; Kankare, Maaria; Bogaerts-Márquez, María; Haudry, Annabelle; Waidele, Lena; Kozeretska, Iryna; Pasyukova, Elena G.; Loeschcke, Volker; Pascual, Marta; Vieira, Cristina P.; Serga, Svitlana; Montchamp-Moreau, Catherine; Abbott, Jessica; Gibert, Patricia; Porcelli, Damiano; Posnien, Nico; Sánchez-Gracia, Alejandro; Grath, Sonja; Sucena, Élio; Bergland, Alan O.; Guerreiro, Maria Pilar Garcia; Onder, Banu Sebnem; Argyridou, Eliza; Guio, Lain; Schou, Mads Fristrup; Deplancke, Bart; Vieira, Cristina; Ritchie, Michael G.; Zwaan, Bas J.; Tauber, Eran; Orengo, Dorcas J.; Puerma, Eva; Aguadé, Montserrat; Schmidt, Paul S.; Parsch, John; Betancourt, Andrea J.; Flatt, Thomas; González; Josefa;
Genomic analysis of European Drosophila melanogaster populations reveals longitudinal structure, continent-wide selection, and previously unknown DNA viruses
Abstract Genetic variation is the fuel of evolution, with standing genetic variation especially important for short-term evolution and local adaptation. To date, studies of spatio-temporal patterns of genetic variation in natural populations have been challenging, as comprehensive sampling is logistically difficult, and sequencing of entire populations costly. Here, we address these issues using a collaborative approach, sequencing 48 pooled population samples from 32 locations, and perform the first continent-wide genomic analysis of genetic variation in European Drosophila melanogaster . Our analyses uncover longitudinal population structure, provide evidence for continent-wide selective sweeps, identify candidate genes for local climate adaptation, and document clines in chromosomal inversion and transposable element frequencies. We also characterise variation among populations in the composition of the fly microbiome, and identify five new DNA viruses in our samples.
Spain, Spain, France, United Kingdom, Denmark, Spain, Italy, Germany, Italy, Germany, Netherlands, Finland, United Kingdom, Italy
- University of Lyon System France
- University of Lausanne Switzerland
- University of Lisbon Portugal
- École Polytechnique Fédérale de Lausanne EPFL Switzerland
- Russian Academy of Sciences Russian Federation
adaptation, demography, Male, demography, QH301 Biology, Acclimatization, Ecology and Evolutionary Biology, ADN, Genome, Insect, adaptation, Adaptation; Clines; Demography; Population genomics; Selection; SNPs; Structural variants; Acclimatization; Altitude; Animals; DNA Viruses; Drosophila melanogaster; Europe; Genome, Mitochondrial; Haplotypes; Insect Viruses; Male; Phylogeography; Polymorphism, Single Nucleotide; Genome, Insect; Genomic Structural Variation; Microbiota; Selection, Genetic, SDG 13 - Climate Action, Ekologia ja evoluutiobiologia, Ecology, Altitude, Microbiota, Clines, geneettinen muuntelu, clines, Europe, Phylogeography, Drosophila melanogaster, populaatiogenetiikka, SNPs, 570, population genomics, Evolution, mahlakärpäset, Settore BIO/18 - GENETICA, Drosòfila melanogaster, selection, Insect Viruses, Polymorphism, Single Nucleotide, 576, QH301, Behavior and Systematics, [SDV.BID.EVO] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], Genetics, Adaptation, demography, Animals, Adaptation, Selection, Genetic, Acclimatization/genetics; Altitude; Animals; DNA Viruses; Drosophila melanogaster/genetics; Drosophila melanogaster/virology; Europe; Genome, Insect; Genome, Mitochondrial; Genomic Structural Variation; Haplotypes; Insect Viruses; Male; Microbiota; Phylogeography; Polymorphism, Single Nucleotide; Selection, Genetic; SNPs; adaptation, demography; clines; population genomics; selection; structural variants, Molecular Biology, Selection, Ecology, Evolution, Behavior and Systematics, Discoveries, Demography, ta1184, DNA Viruses, structural variants, DAS, DNA, Haplotypes, perimä, Genome, Mitochondrial, Genomic Structural Variation, ta1181, Population genomics, Structural variants, Genètica
adaptation, demography, Male, demography, QH301 Biology, Acclimatization, Ecology and Evolutionary Biology, ADN, Genome, Insect, adaptation, Adaptation; Clines; Demography; Population genomics; Selection; SNPs; Structural variants; Acclimatization; Altitude; Animals; DNA Viruses; Drosophila melanogaster; Europe; Genome, Mitochondrial; Haplotypes; Insect Viruses; Male; Phylogeography; Polymorphism, Single Nucleotide; Genome, Insect; Genomic Structural Variation; Microbiota; Selection, Genetic, SDG 13 - Climate Action, Ekologia ja evoluutiobiologia, Ecology, Altitude, Microbiota, Clines, geneettinen muuntelu, clines, Europe, Phylogeography, Drosophila melanogaster, populaatiogenetiikka, SNPs, 570, population genomics, Evolution, mahlakärpäset, Settore BIO/18 - GENETICA, Drosòfila melanogaster, selection, Insect Viruses, Polymorphism, Single Nucleotide, 576, QH301, Behavior and Systematics, [SDV.BID.EVO] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], Genetics, Adaptation, demography, Animals, Adaptation, Selection, Genetic, Acclimatization/genetics; Altitude; Animals; DNA Viruses; Drosophila melanogaster/genetics; Drosophila melanogaster/virology; Europe; Genome, Insect; Genome, Mitochondrial; Genomic Structural Variation; Haplotypes; Insect Viruses; Male; Microbiota; Phylogeography; Polymorphism, Single Nucleotide; Selection, Genetic; SNPs; adaptation, demography; clines; population genomics; selection; structural variants, Molecular Biology, Selection, Ecology, Evolution, Behavior and Systematics, Discoveries, Demography, ta1184, DNA Viruses, structural variants, DAS, DNA, Haplotypes, perimä, Genome, Mitochondrial, Genomic Structural Variation, ta1181, Population genomics, Structural variants, Genètica
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).131 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Top 1% influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Top 10% impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Top 1% views 462 downloads 306 - 462views306downloads
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This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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