Physiopathology of Lifestyle Interventions in Non-Alcoholic Fatty Liver Disease (NAFLD)

descriptionPublicationkeyboard_double_arrow_right Article , Conference object , Review 12 Nov 2020 English Publisher:MDPI AGJournal:Nutrients, volume 12, page 3,472 (eissn: 2072-6643,

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Authors: David Carneros; Guillermo López-Lluch; Matilde Bustos;

doi: 10.3390/nu12113472

pmid: 33198247

pmc: PMC7697937

handle: 20.500.12105/25272 , 10261/230492 , 10668/3646

Physiopathology of Lifestyle Interventions in Non-Alcoholic Fatty Liver Disease (NAFLD)

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Abstract

Non-alcoholic fatty liver disease (NAFLD) is a major health problem, and its prevalence has increased in recent years. Diet and exercise interventions are the first-line treatment options, with weight loss via a hypocaloric diet being the most important therapeutic target in NAFLD. However, most NAFLD patients are not able to achieve such weight loss. Therefore, the requisite is the investigation of other effective therapeutic approaches. This review summarizes research on understanding complex pathophysiology underlying dietary approaches and exercise interventions with the potential to prevent and treat NAFLD.

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Keywords

Medical Subject Headings::Psychiatry and Psychology::Behavior and Behavior Mechanisms::Psychology, Social::Life Style, fasting, Diet, Reducing, Physical exercise, Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Growth::Body Size::Body Weight::Body Weight Changes::Weight Loss, Medical Subject Headings::Phenomena and Processes::Musculoskeletal and Neural Physiological Phenomena::Musculoskeletal Physiological Phenomena::Musculoskeletal Physiological Processes::Movement::Motor Activity::Exercise, Fasting, Review, Medical Subject Headings::Diseases::Digestive System Diseases::Liver Diseases::Fatty Liver, Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Nutrition Therapy::Diet Therapy::Diet, Reducing, Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans, physical exercise, Non-alcoholic Fatty Liver Disease, NAFLD, Weight Loss, Humans, Exercise, Life Style

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