Dairy Products and Dairy-Processing Environments as a Reservoir of Antibiotic Resistance and Quorum-Quenching Determinants as Revealed through Functional Metagenomics

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 11 Feb 2020 Ireland, Ireland, Spain, Australia English Publisher:American Society for MicrobiologyJournal:mSystems, volume 5 (eissn: 2379-5077,

Copyright policy )Publicly fundedFunded by:SFI | Alimentary Pharmabiotic C..., SFI | Determinants of Mother-to..., SFI | New weapons to fight old ...

Authors: Elena A. Alexa; Calum J. Walsh; Laura M. Coughlan; Amal Awad; C Simon; Lorena Ruíz; Fiona Crispie; +2 Authors

doi: 10.1128/msystems.00723-19 , 10.60692/s30md-qje31 , 10.60692/nanap-zrt30

pmid: 32071160

pmc: PMC7029220

handle: 10261/222993 , 10612/21012 , 10147/630421 , 11019/3727 , 11343/305698

Dairy Products and Dairy-Processing Environments as a Reservoir of Antibiotic Resistance and Quorum-Quenching Determinants as Revealed through Functional Metagenomics

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Abstract

The study shows the potential of functional metagenomics analyses to uncover the diversity of functions in microbial communities prevailing in dairy products and their processing environments, evidencing that lactic acid bacteria (LAB) dominate the cheese microbiota, whereas Gram-negative microorganisms of animal or soil origin dominate the microbiota of milk and cheese-processing environments. The functional and in silico screening of the library allowed the identification of LAB, and especially Lactococcus lactis , as a relevant reservoir of antimicrobial resistance (AR) determinants in cheese. Quorum-quenching (QQ) determinants were not recovered through the execution of wet-lab function-based screenings but were detected through in silico sequencing-based analyses.

Countries

Ireland, Ireland, Spain, Australia

Related Organizations

Spanish National Research Council
Spain
Teagasc Food Research Centre
Ireland
University of Leon
Spain
University of Melbourne
Australia
University College Cork (Department of Computer Science)
Ireland

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Keywords

antibiotic resistance, 3309 Tecnología de Los Alimentos, Antibiotic resistance, Tecnología de los alimentos, Metagenomic Analysis, functional metagenomics, Quorum quenching, Gene, 630, Agricultural and Biological Sciences, Antibiotics, Business, Ecology, Biofilm, Probiotics and Prebiotics, Life Sciences, Diversity and Function of Gut Microbiome, QR1-502, food safety, Quorum sensing, Physical Sciences, Quorum Quenching, Research Article, Biotechnology, 570, End hunger, achieve food security and improved nutrition and promote sustainable agriculture, Microbiology, Food safety, http://metadata.un.org/sdg/2, Biochemistry, Genetics and Molecular Biology, Genetics, Molecular Biology, Biology, FOOD SAFETY, Bacteria, dairy products, Resistance (ecology), Ecology and Evolution of Viruses in Ecosystems, FOS: Biological sciences, Environmental Science, Next-generation sequencing, quorum quenching, Functional metagenomics, β-Lactam antibiotics, Metagenomics, Dairy products, Food Science

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