Sensory processing sensitivity has been determined as a personality trait featured by the perception, processing, and interpretation of internal and external stimuli. Thus, this trait has been considered by some recent research studies from different frameworks. Although it exists a lack of accuracy in terminology, some articles have demonstrated that sensitivity of sensory processing may not be considered as a disorder. Therefore, this trait shows different ways to be manifested in some life spheres: physical, cognitive, emotional and interpersonal. In fact, in each sphere we can find several characteristics of sensory processing sensitivity and its manifestation depending on the level. Despite in some cases this trait has been associated with poor well-being, health and quality of life, research reports that sensitivity has a variety of degrees resulting in positive outcomes in general population. This chapter will present a definition of sensory processing sensitivity, a summary of high sensitivity characteristics, some theoretical approaches and recommendations for parents and teachers who are in contact to children with high sensitivity.