The present study was conducted to determine antimicrobial activity of peels extract of two Citrus fruits viz ., C itrus sinensis and C itrus aurantium . The peels were separated from fruits, shade dried, powdered and extracted using methanol. Antibacterial and antifungal activity of peel extracts was determined by agar well diffusion assay and poisoned food technique respectively . Among bacteria, Klebsiella pneumoniae and Bacillus cereus were inhibited to high and least extent respectively. C. sinensis peel extract had marked antibacterial activity than C. aurantium peel extract. In case of antifungal activity, C. aurantium inhibited mycelial growth of Colletotrichum capsici to high extent when compared to C. sinensis . The peel extracts of selected citrus fruits can be used against infectious agents and to control anthracnose of chilli caused by C. capsici .