Objective Proper breastfeeding and weaning practices are effective ways of reducing childhood morbidity and mortality. This study aimed to find out breastfeeding and weaning practices among infants of six months to one year in urban slums of Bahawalpur city. By evaluating the knowledge and attitude of lactating mothers regarding their child feeding habits, modifications and specific interventions can be implemented to improve the breastfeeding and weaning practices of the area. Methods A cross-sectional descriptive study was carried out in the Shahdrah slums of Bahawalpur City after getting approval from the institutional review board of Quaid-e-Azam Medical College, Bahawalpur. The survey was conducted from April 10, 2017 to May 30, 2017. One hundred mothers of infants aging six months to one year of age were interviewed. Mothers filled a customized questionnaire, consisting of questions about logistic variables, breastfeeding, and weaning. Statistical analysis was performed using Statistical Package for the Social Sciences (SPSS) version 22.0 (IBM Corp. Armonk, NY, USA). Results The mean age of the women was 24+2 years. It was found that 74% (n=74) of the mothers had one to three children, 85% (n=85) of the mothers were breastfeeding their infants at the time of the study, 40% (n=40) of the mothers were illiterate, 16% (n=16) of the mothers had secondary education, and 87% (n=87) of the mothers were nonworking women. Out of 85 women who were breastfeeding, 95% (n=80) of the women were 18-23 years of age. We found that 57% (n=57) of the infants were six to nine months old and the remaining 43% (n=43) were up to 12 months of age. Regarding the initiation of breastfeeding, 60% of the females started soon after delivery, and 32% started within two to seven days. We found that 70% (9/13) of the working women and 87.4% (76/87) of the non-working women were breastfeeding. The study found that 92.3% (12/13) of the working women and 88.5% (77/87) of the non-working women were weaning. Conclusion A majority of the mothers were breastfeeding and weaning their babies. The factors documented were young age, low parity, no working status, and nuclear families. The commonly used feeding materials were cereals, banana, rice, and bread. No side effects of weaning were observed. Weaning was associated by late age, parity, non-working status, educational status of father, and nuclear families.