Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Journal of Medicinal...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
Journal of Medicinal Plants Research
Article . 2014 . Peer-reviewed
Data sources: Crossref
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
Journal of Medicinal Plants Research
Article
License: CC BY
Data sources: UnpayWall
https://dx.doi.org/10.60692/k3...
Other literature type . 2014
Data sources: Datacite
https://dx.doi.org/10.60692/79...
Other literature type . 2014
Data sources: Datacite
versions View all 3 versions
addClaim

Exploration of the anti-diabetic effect of the matured seeds of Dioclea reflexa

English
Authors: Adeyinka Gk Adepoju; OJ Balogun;

Exploration of the anti-diabetic effect of the matured seeds of Dioclea reflexa

Abstract

El estudio tuvo como objetivo explorar el efecto antidiabético de la harina de semilla de Dioclea reflexa en ratas diabéticas inducidas por aloxanina. Treinta ratas Wistar de ambos sexos fueron expuestas a dosis respectivas de la harina de semilla y los medicamentos estandarizados (Gliclazida 6.1 mg/kd de peso corporal y Metformina 60 mg/kg de peso corporal) de acuerdo con las especificaciones del grupo. Se encontró que la harina de semilla a una dosis de 2 g/kg de peso corporal por vía oral una vez al día era más efectiva que cualquiera de los medicamentos estándar con los que se comparó. El resultado mostró que la harina de semilla de D. reflexa poseía una potente propiedad hipoglucémica oral probablemente mediada por una mayor utilización periférica de glucosa.

L'étude visait à explorer l'effet antidiabétique de la farine de graines de Dioclea reflexa sur les rats diabétiques induits par l'alloxan. Trente rats Wistar des deux sexes ont été exposés à des doses respectives de la farine de graines et des médicaments standardisés (Gliclazide 6,1 mg/kd de poids corporel et Metformine 60 mg/kg de poids corporel) selon les spécifications du groupe. La farine de graines à une dose de 2 g/kg de poids corporel par voie orale une fois par jour s'est avérée plus efficace que tous les médicaments standard avec lesquels elle a été comparée. Le résultat a montré que la farine de graines de D. reflexa possédait une puissante propriété hypoglycémique orale probablement médiée par une utilisation périphérique accrue du glucose.

The study aimed at exploring the anti-diabetic effect of the seed flour of Dioclea reflexa on alloxaninduced diabetic rats.Thirty Wistar rats of both sexes were exposed to respective doses of the seed flour and the standardized drugs (Gliclazide 6.1 mg/kd body weight and Metformin 60 mg/kg body weight) according to the group specifications.The seed flour at a dose of 2 g/kg body weight per oral once daily was found to be more effective than any of the standard drugs with which it was compared.The result showed that D. reflexa seed flour possessed potent oral hypoglycaemic property probably mediated via increased peripheral utilization of glucose.

هدفت الدراسة إلى استكشاف التأثير المضاد للسكري لدقيق بذور Dioclea reflexa على الفئران المصابة بالسكري التي يسببها alloxanan. تم تعريض ثلاثين فأرًا من كلا الجنسين لجرعات خاصة من دقيق البذور والأدوية الموحدة (Gliclazide 6.1 ملجم/كجم من وزن الجسم و Metformin 60 ملجم/كجم من وزن الجسم) وفقًا لمواصفات المجموعة. تم العثور على دقيق البذور بجرعة 2 جم/كجم من وزن الجسم عن طريق الفم مرة واحدة يوميًا ليكون أكثر فعالية من أي من الأدوية القياسية التي تمت مقارنتها بها. أظهرت النتيجة أن دقيق بذور D. Reflexa يمتلك خاصية قوية لنقص السكر في الدم عن طريق الفم ربما عن طريق زيادة الاستخدام المحيطي للجلوكوز.

Related Organizations
Keywords

Polymers and Plastics, Endocrinology, Diabetes and Metabolism, Materials Science, Plant Science, Agricultural and Biological Sciences, Food science, Diabetes, Oxidative Stress, and Antioxidants, Synthesis and Characterization of Polymer Resins, Diabetes mellitus, Endocrinology, Health Sciences, Alloxan, Internal medicine, Pharmacology, Diabetes, Life Sciences, Traditional medicine, Body weight, Metformin, Oral administration, Chemistry, Medicinal and Poisonous Plants in Brazil, Gliclazide, Physical Sciences, Oral dose, Medicine

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    1
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
1
Average
Average
Average
gold