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African Journal of Biotechnology
Article . 2010 . Peer-reviewed
Data sources: Crossref
https://dx.doi.org/10.60692/cc...
Other literature type . 2010
Data sources: Datacite
https://dx.doi.org/10.60692/xc...
Other literature type . 2010
Data sources: Datacite
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Evaluation of antioxidant potential of medicinal plants from Malaysian Rubiaceae (subfamily Rubioideae)

English
Authors: Rohaya Ahmad; Emi Norzehan Mohamad Mahbob; Zainon Mohd Noor; Nor Hadiani Ismail; Lajis; H N; Khozirah Shaari;

Evaluation of antioxidant potential of medicinal plants from Malaysian Rubiaceae (subfamily Rubioideae)

Abstract

Este documento evalúa el potencial antioxidante de 22 especies de plantas medicinales de Rubiaceae de Malasia. Se emplearon los ensayos de tiocianato férrico (FTC), ácido tiobarbitúrico (TBA), contenido fenólico total (TPC) y 1,1-difenil-2-picrilhidrazilo (DPPH). Los extractos probados mostraron un fuerte potencial antioxidante en comparación con hidroxitolueno butilado (BHT), quercetina y vitamina E con un porcentaje de inhibición del 91 -99% en el FTC y del 77 -97% en los ensayos de TBA. El TPC de los extractos encontrados varió de 8,55 a 120,63 mg de GAE /g de PE. Psychotria griffithii y Hydnophytum formicarum mostraron un contenido fenólico total de más de 100 mg de GAE/gPE y una fuerte actividad de eliminación de radicales DPPH con valores de IC 50 de 14,0 y 22,4 µg/ml, respectivamente. La vitamina C estándar y BHT mostraron valores de IC 50 de 12,8 y 5,6 µ µg/ml, respectivamente. Se observó una buena correlación entre el contenido fenólico total y las actividades de eliminación de radicales. Se espera que las plantas analizadas en este estudio sean buenas fuentes de antioxidantes naturales.

Cet article évalue le potentiel antioxydant de 22 espèces de plantes médicinales de Rubiacées malaisiennes. Le thiocyanate ferrique (FTC), l'acide thiobarbiturique (TBA), la teneur phénolique totale (TPC) et les tests 1,1-diphényl-2-picrylhydrazyl (DPPH) ont été utilisés. Les extraits testés ont montré un fort potentiel antioxydant par rapport à l'hydroxytoluène butylé (BHT), à la quercétine et à la vitamine E avec un pourcentage d'inhibition de 91 à 99% dans le FTC et de 77 à 97% dans les tests TBA. Le TPC des extraits trouvés variait de 8,55 à 120,63 mg GAE /g PE. Psychotria griffithii et Hydnophytum formicarum ont montré une teneur phénolique totale supérieure à 100 mg GAE/gPE et une forte activité anti-radicalaire DPPH avec des valeurs IC 50 de 14,0 et 22,4 µg/ml, respectivement. La vitamine C standard et BHT ont montré des valeurs IC 50 de 12,8 et 5,6 µ µg/ml, respectivement. Une bonne corrélation a été observée entre la teneur phénolique totale et les activités anti-radicalaires. Les plantes médicinales de cette étude devraient être testées comme de bonnes sources d'antioxydants naturels.

This paper evaluates the antioxidant potential of 22 species of medicinal plants from Malaysian Rubiaceae.The ferric thiocyanate (FTC), thiobarbituric acid (TBA), total phenolic content (TPC) and the 1,1-diphenyl-2-picrylhydrazyl (DPPH) assays were employed.The tested extracts showed strong antioxidant potential when compared to butylated hydroxytoluene (BHT), quercetin and vitamin E with percent inhibition of 91 -99% in the FTC, and 77 -97% in the TBA assays.The TPC of extracts found varied from 8.55 to 120.63 mg GAE /g PE .Psychotria griffithii and Hydnophytum formicarum showed total phenolic content of more than 100 mg GAE/gPE and strong DPPH radical-scavenging activity with IC 50 values of 14.0 and 22.4 µg/ml, respectively.The standard vitamin C and BHT showed IC 50 values of 12.8, and 5.6 µ µ µ µg/ml, respectively.A good correlation was observed between total phenolic content and radical-scavenging activities.The medicinal plants in this study tested are expected to be good sources of natural antioxidants.

تقيّم هذه الورقة إمكانات مضادات الأكسدة لـ 22 نوعًا من النباتات الطبية من الروبياسي الماليزية. ثيوسيانات الحديد (FTC) وحمض الثيوباربيتوريك (TBA) والمحتوى الفينولي الكلي (TPC) ومقاييس 1،1 -ثنائي فينيل-2 -بيكريل هيدرازيل (DPPH). أظهرت المستخلصات المختبرة إمكانات مضادات الأكسدة القوية عند مقارنتها بالهيدروكسيتولوين البوتيلاتي (BHT) والكيرسيتين وفيتامين E مع تثبيط بنسبة 91 -99 ٪ في FTC، و 77 -97 ٪ في فحوصات TBA. أظهرت TPC من المستخلصات التي تم العثور عليها من 8.55 إلى 120.63 ملغ GAE/GE. أظهرت Psychotria griffithii و Hydnophytum formicarum إجمالي المحتوى الفينولي لأكثر من 100 ملغ GAE/GPE ونشاط مسح جذري DPPH قوي مع قيم IC 50 من 14.0 و 22.4 ميكروغرام/مل، على التوالي. أظهر معيار فيتامين C و BH قيم ICT من 12.8 و 5 ميكرو ميكرو ميكروغرام/ملليلتر على التوالي. لوحظ محتوى جيد من الكورتين بين إجمالي الأنشطة الجذرية والطبية. ومن المتوقع أن تكون هذه المصادر الطبيعية لمضادات الأكسدة الجيدة.

Keywords

Thiobarbituric acid, Pharmacology, Toxicology and Pharmaceutics, medicinal value, Lipid peroxidation, Organic chemistry, Plant Science, Biochemistry, Agricultural and Biological Sciences, Food science, Health Sciences, Pharmacological Aspects of Psidium guajava, Vitamin C, Biology, Pharmacology, Medicinal Plants: Chemical Constituents and Biological Activities, Antioxidants and Free Radicals in Health and Disease, Botany, Life Sciences, Traditional medicine, Antioxidant, Rubiaceae, ferric thiocyanate (FTC), thiobarbituric acid (TBA), 1,1-diphenyl-2-picrylhydrazyl (DPPH), total phenolic content (TPC), Chemistry, Butylated hydroxytoluene, Medicine, Quercetin, Antioxidant, DPPH

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
11
Average
Average
Average
gold