This chapter explores the impact of the Great Depression on women students at UK. To support financially strapped women students the university utilized several New Deal student work programs and established group houses where women students could live more frugally. Highlighted are the contradictions between women’s academic aspirations and successes and their vocational and educational opportunities after college, made even more problematic by the worsening economic conditions. Combining a career with marriage remained almost impossible for most women college graduates. Moreover, women students still had to endure both subtle and obvious sex discrimination in the classroom. Also discussed is the establishment of a women’s building on campus, where women students and faculty could gather and where women’s organizations could meet. By the end of the 1930s the Woman’s Building was closed with the opening of a new student union.