Metacognition is an important aspect of learning because metacognition affects a person’s learning process. Metacognition is also a strong predictor of academic success and problem solving. To improve students’ metacognition skills, appropriate learning strategies are needed. Metacognitive learning strategy is one strategy that has the potential to improve students’ metacognitive abilities. This study aims to produce metacognitive learning strategy. The research design used is Research and Development, which refers to the 4D development model from Thiagarajan, namely Define, Design, Develop, and Disseminate. The define, design, and develop stages produce valid, practical, and effective metacognitive learning strategy. Validation of learning strategy and tools was carried out by three experts in the field of chemistry education. The development of metacognitive learning strategy was carried out through limited trials and implementation was carried out on the undergraduate students of Chemistry Education Study Program in Malang Indonesia, in the Organic Chemistry I course. The resulting metacognitive learning strategy is called PDCA Metacognitive Learning Strategy (Preparing, Doing, Checking, and Assessing & Following-Up).