This chapter summarizes the recent advances in additive manufacturing of high-strength aluminum alloys, the challenges of printability, and defects in their builds. It further intends to provide an overview of the state of the art by outlining potential strategies for the fabrication of bulk products using these alloys without cracking. These strategies include identifying a suitable processing window of additive manufacturing using metallic powders of conventional high-strength aluminum alloys, pre-alloying the powders, and developing advanced aluminum-based composites with reinforcements introduced either by in situ or ex situ methods. The resulting microstructures and the relationship between these alloys’ microstructure and mechanical properties have been discussed. Since post-processing is inevitable in several critical applications, the chapter concludes with a brief account of post-manufacturing heat treatment processes of additively manufactured aluminum alloys.