Diabetes mellitus is a disorder in which blood sugar (glucose) levels are abnormally high because the body does not produce enough insulin to meet its needs. The world population with Diabetes mellitus is estimated to be about 387 million and may reach 471 million in 2035. Diabetes is, therefore, considered to be the most common endocrine disease. There is significant evidence supporting the idea of interventions to improve diabetes outcomes, one of them is glycemic control in the basic nutrition. Coconut sugar (Cocos nuciferas. L.), has been marketed with the promise of having a low glycemic index and recommended for diabetic patients. This research's objective was to compare the glycemic response of 30 healthy volunteers in 4-hour fasting after the intake of coconut sugar, sucrose and brown sugar, ranging in age from 19 to 50 years, being 73% female and 27% male, who were randomly divided into three distinct groups with the intake of 50g of the respective sugars. Capillary blood glucose was measured in times: 0; 15; 30; 45 and 60 minutes. The data was evaluated using the analysis of variance, and the Scott-Knott test was chosen to verify the differences in results. We conclude that the three kinds of sugars presented statistically the same behaviors (p <0.05) regarding the increase of glycemia in times 15, 30 and 60 minutes in relation to time zero, there was a significant difference (p <0.05) in the time of 45 minutes, where a longer time for the coconut sugar decrease occurred. However, it is concluded that coconut sugar behaves similarly to the other sugars, and should be re-evaluated as a product that has a low glycemic index.