This book presents the results over the influence of the implementation of an interactive multimedia CD in Adobe Animate Flash to facilitate English vocabulary learning in students of first level of the extension of the language center in ESPOCH. A pre-test was applied to the experimental group and the control group to determine their level of knowledge of English vocabulary and some basic rules for forming new words. This study allowed to determine the greatest difficulties that students have when identifying new vocabulary. After a period of experimentation implementing the interactive multimedia CD in Adobe Animate Flash with the experimental group; a post-test was reapplied for both groups to see if there was any effect. When analyzing the data of the results obtained in the post-test it was possible to verify the improvement in vocabulary learning in the students of the experimental group, reason why it was proceeded to propose the workshop of creation and management of the interactive multimedia CD in Adobe Animate Flash, aimed at learning English vocabulary for use of first level teachers of language center extension in ESPOCH.