The Mesoscale Convective Systems (MCSs) produce numerous weather hazards with their variety of forms. The formation mechanism of MCSs is thus important to know for Bangladesh and its surroundings, because this region is one of the heaviest rainfall areas in the tropical zone. The meteorologists are studying and analyzing the formation mechanism of different types of MCSs using radar and satellite observations data. Observations are limited to real time, but for planning purposes projected parameters over a certain period obtained from a mesoscale model is the requirement. Consequently, the motivation of this paper is to obtain the evolution and life cycle of MCSs developed in and around Bangladesh during pre-monsoon period through the simulation by a mesoscale model named MM5. In this work the calibration of MM5 model for different cumulus parameterization has been performed during the pre-monsoon period of this region. In the present study two domains with mesh resolutions 45 km × 45 km and 15 km × 15 km are prepared. MM5 runs using different cumulus parameterizations are carried out for sensitivity test. The precipitation simulated by the model are compared structurally and numerically with that of Tropical Rainfall Measuring Mission (TRMM) data products, available data from radar scan and observed rain-gauges rainfall in Bangladesh. Important features like lifetime, maintenance mechanism, traversed path, propagation speed and direction of MCSs developed during pre-monsoon period of 2002 in and around Bangladesh have been pointed out.