In undergraduate biology education, especially in cell biology, it has been a challenge for students to integrate images well to memorize the complex and scattered expertise. In traditional biology teaching, the teacher's way of explaining with images is not good enough to show the connection between cell structure and function directly. Biology students need to spend long extra time to memorize these very essential points, which not only reduces students' interest in learning, but also is a very painful process for students with poor spatial imagination. However, the newly emerged VR game technology, which is visual, playful, and interactive, can be a good solution to the problem of students' interest in learning and their lack of spatial imagination. According to this situation, this paper designs a VR game as a supplementary teaching tool for cell biology and examines it from seven aspects: game mechanics, visual aesthetics, narrative, motivation, music score, learning objectives, and relevant. With using this VR game, biological related specialized student can directly see the changes in structure and remember them with pleasure, and teachers with similar teaching needs could also use them to improve learning effects. Finally, the advantages and limitations of this teaching aid are evaluated, aiming at broadening the current means of teaching undergraduate biology and providing new ideas for future higher education teaching of cell biology.