We hereby report a detailed design and fabrication of our indigenously developed smart UAV (drone) Ozone, O3, monitoring system, using locally sourced materials in Nigeria. Our device is locally built from scratch to finish using materials available to us. Our design comprises a small lightweight (Polystyrene), Rotors, Arduino Joystick, Arduino Nano Board, 434 MHz Transmitter Module, 1 KΩ Resistor, Vero Board, Connecting wires, 9 Volts Battery, Antenna, simple and cost-effective multi-sensor system for multiple measurements of atmospheric phenomena and related climate information. We have used a long-range wireless communication module with real-time monitoring and visualizing software applications embedded on our device to access live data, track trends, and archive historical data for comparisons (data logger). We have also obtained original ozone datasets after conducting test flight measurement experiments at the launch site (Rivers State University Campus) Port Harcourt, Nigeria.