Biotech-Careers.org is a comprehensive career information resource used in college and high school classrooms nationwide. The site combines education materials and job search capabilities with an extensive employer database. We describe four paths for exploring Biotech-Careers.org–People, Places, Things, and Jobs and describe the impacts of using the site on multiple cohorts of college students. The students reported an increased interest in pursuing biotechnology-related careers and an increase in cognitive factors (awareness, belonging, self-efficacy, and identity) known to be important in career choice.