EDEN ISS is a program funded by the EU having as main goal the development of a greenhouse to be installed in Antarctica at the Neumayer III station to test key technologies for a future space greenhouse. The Antarctic environment has been selected for an analogue test campaign because of its similarity with extraterrestrial outposts, with harsh ambient conditions, and similar limitations on, for example, power, number of human operators, and accessibility. Taking advantage of the limited accessibility and constraints on data transfer between Europe and the Antarctic, EDEN ISS has the objective to test the operation scenario, i.e. the planning of activities, the procedures, and the interaction between on-site and remote operators in a similar scenario as would apply for future planetary bases. One of the key points of the greenhouse performance monitoring is the plant health monitoring, and most of all the early detection of plant disease and the subsequent activation of corrective actions. For that reason, a plant monitoring system is foreseen with the objective of collecting information suitable for analysis by a knowledge system (either local or remote) to assess and advise prophylactic measures to the local operator. As only one operator will handle the system, there is a need for objective assessment of plant welfare and performance, through automatic detection and expert assessment of remote information. This document describes the final layout of the Plant Health Monitoring system. This system differs in several aspects from the one proposed at the CDR. In particular the mobile platform hosting the cameras for lateral views of the plants has been discarded due to budget issues. Nevertheless the capability of lateral image acquisition will be maintained by means of fixed cameras. The system relies on several components: 1. Top view images by a fixed system of visual cameras one for each/two trays 2. One HD-video camera modified for multispectral imaging 3. An automatic image acquisition and distributor system After some local pre-processing of information, the Plant Health Monitoring will provide data to remote experts from different disciplines, in order to implement their feedback into the overall control loop. Some information on the data acquisition and transfer is provided within this document. Aside from plant health monitoring, the on-site operator will have options to control plant health by taking corrective actions to address issues with e.g. nutrient solution composition, environmental conditions or microbial contamination. This document details the equipment which will be available in situ to determine microbial contamination and, if necessary, to decontaminate the facility, to ensure safe and clean food production.