Agriculture and climate change are internally correlated with each other in various aspects, as climate change is the main cause of biotic and abiotic stresses, which have adverse effects on the agriculture of a region. The land and its agriculture are being affected by climate changes in different ways, e.g., variations in annual rainfall, average temperature, heat waves, modifications in weeds, pests or microbes, global change of atmospheric CO2 or ozone level, and fluctuations in sea level. Plant growth and yield are greatly influenced by abiotic stresses. Under natural climate conditions, plants often experience numerous stresses like waterlogging, drought, heat, cold, and salinity. living organisms such as plants, animals, fishes, and humans have been affected by the extreme environmental conditions around the globe. The danger to the world’s climate conditions has triggered anxiety among everyone because crop yield might be compromised by fluctuations in various environmental factors that can risk food security. Recent studies reported that the developed countries have more vulnerability towards climatic changes (8–11%) than developing states. This article explores the various ways in which climate change affects crop production, the region’s most at risk, and the strategies farmers are adopting to mitigate these impacts.