The face of business to business (B2B) commerce is being changed at an significantly accelerating pace by digital technologies which is forcing a paradigm shift in the commonly used business models. This article explores the multifaceted impacts of digital transformation on traditional B2B business models, delineating the most important elements of the digital environment and the opportunities and challenges such an environment creates. Digital initiative, which is a blend of digital technologies into the company operations, is inevitable on a road to a top business establishment. Inside the B2B territory the digital transformation takes form through usage of the e-commerce platforms, data analytics, IoT solutions and other digital tools which are for improvement of processes as well as increase of customers’ value. Realizing the sources of digital disruption that make business transformation possible become a crucial task for those companies who want to undergo successful adaptations. B2B business models characterized with the longstanding relations and cooperation of all defined actors in the chain are taking a big bite out of the digital revolution. E-commerce platforms and marketplaces have revolutionized and transactional relationship, with the provision of upgraded processes and more accessibility options. Besides that, the advent of data analytics and business intelligence is having ripple effect in supply chain management as this enables decision making on real-time basis, and also enhances efficiency in operations. For instance, the interconnected systems created by IoT are also boosting supply chain operations by granting process owners the ability to know what is happening in the inventory, or simply be aware of shipping of commodities and the situation of the assets. While digital revolutions bring positive outcomes, there arise the challenges that privacy should be taken into account when there is technology adoption. Therefore, in a digital world a business has to prepare for seamless integration, personalized experiences and greater transparency. Finally, the competition in the digital market calls for distinguishing your business through innovation, customer centricity, and agility. Despite these difficulties can emerge the possibility of the revenue growth and business model innovation. B2B companies can use digital technologies to explore the new market offerings, widen product offerings, and provide value-added services as well. Developing an innovation-centric and quick-to-adapt culture is apparently the right approach for companies striving to stand the test of time in the emerging world of B2B commerce. The paper provides a case study or an example highlighting the digital transformation that took place in B2B business and documents the crucial aspects which a business should take note of. Whether they are traditional industry leaders or budding startups, any B2B business of all sizes can use digital transformation as the engine of growth and an effective strategic tool to stay ahead of competition.