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Article . 2008
License: CC BY
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Article . 2008
License: CC BY
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Protein Secondary Structure Prediction

Authors: Manpreet Singh; Sandhu, Parvinder Singh; Kaur, Reet Kamal;

Protein Secondary Structure Prediction

Abstract

{"references": ["Cuff, J. A. and Barton, G.J. \"Evaluation and improvement of multiple\nsequence methods for protein secondary structure prediction. Proteins,\n34, 1999, pp. 508-519.", "Cuff, J.A. and Barton G.J. \"Application of multiple sequence alignment\nprofiles to improve protein secondary structure prediction\" Proteins, 40,\n2000, pp. 502-511.", "Jones, D.T. \"Protein secondary structure prediction based on positionspecific\nscoring matrices\" Journal of Molecular Biology, 292, 1999, pp.\n195 -202.", "Kabsch, W. and Sander, C. \"Dictionary of protein secondary structure:\nPattern recognition of hydrogen-bonded and geometrical features\"\nBiopolymers, 22, 1983, pp. 2577-2637.", "Kloczkowski, A., Ting, K.L., Jernigan, R.L. and Garnier, J. \"Combining\nthe GORV algorithm with evolutionary information for protein\nsecondary structure prediction from amino acid sequence\" Proteins, 49,\n2002, pp. 154-166.", "Krane, D. and Raymer, M. (2003), \"Fundamental Concepts of\nBioinformatics\", Pearson Education, New Delhi, pp.1-314.", "Moult, J., Hubbard, T., Bryant, S.H., Fidelis, K. and Pedersen, J.T.\n\"Critical assesment of methods of protein structure prediction (CASP):\nround II\". Proteins, S1, 1992, pp. 2-6.", "Rost, B. and Sander, C. (1993) \"Prediction of protein secondary\nstructure at better than 70% accuracy\" Journal of Molecular Biology,\n232, pp. 584-599.", "Sander, C. and Schneider, R. \"Database of homology-derived structures\nand the structural meaning of sequence alignment\" Proteins, 9, 1991, 56-\n68."]}

Protein structure determination and prediction has been a focal research subject in the field of bioinformatics due to the importance of protein structure in understanding the biological and chemical activities of organisms. The experimental methods used by biotechnologists to determine the structures of proteins demand sophisticated equipment and time. A host of computational methods are developed to predict the location of secondary structure elements in proteins for complementing or creating insights into experimental results. However, prediction accuracies of these methods rarely exceed 70%.

Keywords

Secondary Structure, Protein, DNA, RNA., Prediction

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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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