Good nutrition remains a global public health challenge in both high- and low-income countries. The common “one-size-fits-all" approach in public health nutrition has brought both successes and failures with reducing mortality. Nutritional status and response to interventions are impacted by a variety of factors and we need more precise solutions that address the etiology of conditions. But how do we overcome global malnutrition in a precise, safe, quick, yet inclusive way? PN approaches have been on the rise in high-income countries (HIC) but remain understudied and under implemented to reduce malnutrition in LMIC. Diagnostics and treatments at the individual level are expensive, and capacity is often limited. Nonetheless, we think that prioritizing solutions with high potential for scale-up and impact is our moral obligation. To achieve improved health outcomes in a cost-effective manner, PN in LMIC should focus on tailored nutritional interventions for vulnerable groups that account for many similar biological and socioeconomic factors. Although PN for public health will require significant time, resources and workforces, we have seen that movements such as these are indeed possible in recent years. We believe that PN could be the missing link to advance our efforts towards a world free from malnutrition.