Abstract. In the North Ionian, water circulation is characterized by a decadal alternation of cyclonic and anticyclonic regime driven by the mechanism called BiOS (Bimodal Oscillating System). The circulation regime affects the vertical dynamics and the nutrient distribution. The North Ionian is then a good study area to investigate how changes in circulation can affect phytoplankton dynamics in oligotrophic regions. From in situ observations, for each circulation regime the averaged distribution of isopycnals is provided, and a depth difference of about 80 m is estimated for the nitracline between cyclonic and anticyclonic regime. Based on phytoplankton phenology metrics extracted from annual time-series of satellite ocean color data for the period 1998–2012, the cyclonic and anticyclonic regimes are compared. Results show that the average chlorophyll in March, the date of bloom initiation and the date of maximum chlorophyll were affected by circulation patterns in the North Ionian. In the center of the gyre, bloom initiation occurred in December and chlorophyll was low in March when circulation was anticyclonic, whereas during the cyclonic circulation regime, a late chlorophyll peak, likely resulting from different phytoplankton dynamics, was commonly observed in March. An additional analysis shows that the winter buoyancy losses, which govern the Mixed Layer Depth (MLD) also contribute to explain the interannual variability in bloom initiation and intensity. Two scenarios involving the relative position of the MLD and nitracline are finally developed, discussed and tested with model data to explain the different phenology patterns observed in the North Ionian.