The rapid growth of agriculture and industrial activities has resulted in decreasing of water quality in the aquatic ecosystem, which is significantly hazardous for fish health. Fish are commonly situated at the top of aquatic food chain is known to be nutritious with essential proteins. The purpose of this study is to determine the condition factor and hepatosomatic index of Barbonymus schwanenfeldii from Galas River, Kelantan. The sizes of slaughtered fish ranging from 319 ± 0.05 to 456 ± 1.32 g in weight while 28 ± 0.34 to 36 ± 1.42 cm in total length. From a sample size of 40 specimens, the average of K value was 1.15 ± 0.21 and 2.31 ± 0.13 of HSI value. Thus, the results revealed that the fish species was in a poor condition. Refer to the matter; the condition of study area is not suitable for fish habitat. Condition factor of fishes is important biological parameter which can provides information on fish well-being. The condition factor and hepatosomatic index compares the well-being of a fish is based on the hypothesis that heavier fish of a given length are in a better condition.