The related issues to trade liberalization and its impact on the environmental quality have become important since late 1996. The previous studies have shown that there has not been consensus among the economists in this field. Paper is analyzing the effect of inter-industrial trade on the Iran’s air pollution. Also in this paper, the pollution haven hypothesis is tested in Iran. To study the effect of inter-industrial trade on the environment in two ways: 1) direct effect on the environment and 2) an indirect effect through growth and the effect of growth on the environment were examined. The model has been estimated by using the panel data method for Iran’s various industrial sectors over 1980-2014. The results show that inter-industrial trade has positive effect on Iran’s air pollution. Also, pollution haven hypothesis is valid in Iran.