Let R be a prime ring, I a nonzero ideal of R and n a fixed positive integer. If R admits a generalized derivation F associated with a derivation d such that c for all x, . Then either R is commutative or n = 1, d = 0 and F is the identity map on R. Moreover in case R is a semiprime ring and for all x, , then either R is commutative or n = 1, , R contains a non-zero central ideal and for all .